We are part of the team being awarded the H2020 Marie Skłodowska-Curie Actions (MSCA) Innovative Training Networks (ITN) with the project “STOP SPREAD BAD BUGS: novel antimicrobial approaches to combat multidrug resistance in bacteria“. As part of the CONCEPT lab we will support a multidisciplinary team composed by medical doctors, biologists, chemists, and physicists to […]
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We are part of the PRIN 2020 project CANNOT-ESKAPE!
We are part of the team being awarded the national PRIN2020 project “CANNOT-ESKAPE: Targeting baCteriAl cell eNvelope of Nocosomial paThogens to ESKAPE resistance”. Our unit, led by Rita de Zorzi (University of Trieste), we will support a multidisciplinary team led by Flavia Squeglia (CNR, Naples), supporting biologists, chemists, and physicists tackling the problem of antimicrobial […]
Read our latest paper on the topology to employ for in silico designed peptides!
A new application of BINDesignER/PARCE! Herein, we compared the ability of linear and cyclic peptides generated in silico to target different protein sites: internal pockets and solvent-exposed sites. We selected human lysozyme (HuL) as a model target protein combined with the computational evolution of linear and cyclic peptides. The computational results demonstrated that cyclic peptides […]
Welcome to Patricio Barletta, who joined today our AIRC research project.
We welcome Patricio Barletta in our team! Patricio got his PhD from the Universidad Nacional de Quilmes, Argentina in 2020 and joined our team in the framework of the ICTP-TRIL fellowship program. He will work on the computational aspects of our project. He will carry out his activity in the CONCEPT Lab head by Walter […]
We have been awarded a “ARDF’s Annual Open grant” from the Alternatives Research & Development Foundation (ARDF)
Our commitment in the development of new computational protocols that can compete and, in time, eliminate the demand for in vivo procedures for antibody discovery and maturation has been prized once again with a 40,000$ grant with the project ” De-novo engineered antibody fragments: validation of the first in-silico pipeline for antibody discovery ” from the […]
Welcome to Theo Battista, who joined today our AIRC research project.
We welcome Theo Battista in our team! Theo just got his PhD in Biochemistry from “Sapienza”, University of Rome. He will carry out his activity at the Structural Biology Lab head by Paola Storici at Elettra, Trieste, Italy.
Siamo stati in onda sul TG Leonardo!
Nell’ambito di una collaborazione con Trasactivia SrL e l’Universita’ Tor Vergata di Roma stiamo contribuendo allo sviluppo di un nuovo vaccino prodotto interamente dalle foglie delle piante di tabacco. Il progetto e’ stato presentato su Rai3 nell’ambito del TG Leonardo. Ci trovate al minuto 8.51 -11.31
JOIN US! We are HIRING!
WE ARE HIRING!!! We are looking for two postdoctoral researchers: a biologist and a computational chemist/biophysicist to join us reaching the goal of our new AIRC project. Please follow THIS LINK for further details on each position.
UniTS press release on our latest AIRC project
The University of Trieste celebrated our achievements HERE (post available only in Italian), and also on FACEBOOK and LinkedIn!
Read our latest paper on in silico designed peptides for nanopatterned surface sensors!
We present a rationally designed, self-assembled nanochip capable of capturing a target protein by means of pre-selected binding sites. We show how the confined peptides are capable of specifically capturing β2m from the surface–liquid interface with micromolar affinity, hence providing a viable proof-of-concept for our approach to peptide design A. Feyisara Adedeji Olulana, M.A. […]