We have identified a strong diazepane based σR ligand with high affinity, low cytotoxicity, and excellent antioxidant profile.

For further details, read our paper here:
D. Zampieri, S. Fortuna, A. Calabretti, M. Romano, R. Menegazzi, D. Schepmann, B. Wünsch, M.G. Mamolo
Synthesis, Cytotoxicity Evaluation and Computational Insights of Novel 1,4-Diazepane-Based Sigma Ligands
ACS Med. Chem. Lett., 2020, in press.