We have identified a strong diazepane based σR ligand with high affinity, low cytotoxicity, and excellent antioxidant profile. For further details, read our paper here: D. Zampieri, S. Fortuna, A. Calabretti, M. Romano, R. Menegazzi, D. Schepmann, B. Wünsch, M.G. Mamolo Synthesis, Cytotoxicity Evaluation and Computational Insights of Novel 1,4-Diazepane-Based Sigma Ligands ACS Med. Chem. […]
Our paper “A consensus protocol for the in silico optimisation of antibody fragments” has just been accepted for publications, marking the first milestone of our AIRC project “Computational design of customised nanobodies for oncology applications: prognostic candidates for HER2 as first case”. In this paper we present BINDesignER: our in silico mutagenetic protocol for the […]
Our commitment in the development of new computational protocols that can compete and, in time, eliminate the demand for in vivo procedures for antibody discovery and maturation has been prized with a 40,000$ grant with the project “In silico design of customised high-affinity antibody fragments for biomarker detection” from the Alternatives Research & Development Foundation […]
We joined a HUGE multidisciplinary collaborating network (that also includes the group of J.E. Rothman, 2013 Nobel Prize in Medicine!!) and we published on the American Journal of Human Genetics (achievement also covered by a press release and distributed, among others, by ANSA, national press IlMessagero, and TV TELENORD). Here the paper (and play the […]
Our paper Influence of Molecule-Surface and Molecule-Molecule Interactions on Two-Dimensional Patterns formed by Functionalised Aromatic Molecules is featured on the cover of the Journal of Physical Chemistry C. The Image was created and rendered with POV-Ray. Actually POV-Ray feels a lot as a scripting language as it is quite easy to code, but it is also […]
JOIN US at the IOP Workshop: Self-Assembly, Recognition, and Applications (SARA) 2017, Univeristy of Lincoln UK, 14 December 2017 (deadline: 21 November 2017 ) We would like to bring to your attention the IOP workshop “Self–Assembly, Recognition, and Applications (SARA) 2017” which will be held on 14 December 2017 at the University of Lincoln […]
Sara Fortuna has been awarded an AIRC MFAG research grant from the Italian Association for Cancer Research (AIRC) (225,00€, 3 years) with the project “Computational design of customised nanobodies for oncology applications: prognostic candidates for HER2 as first case”
Sara Fortuna has been awarded a RSC Research Fund Grant from the Royal Society of Chemistry (UK) (2,700£) with the project “Computational design of bidentate binders of increased affinity and selectivity”
JOIN US at the IOP Workshop: Self-Assembly, Recognition, and Applications (SARA) 2016, Univeristy of Edinburgh, UK, 9 December 2016 (deadline: 21 November 2016 ) We would like to bring to your attention the IOP workshop “Self-assembly, recognition and applications” which will be held on 9 December 2016 at the University of Edinburgh. The ability […]
